CALL FOR PAPERS Real-Time Visualization of Lung Function: From Micro to Macro Mechanical ventilation causes airway distension with proinflammatory sequelae in mice

نویسندگان

  • Hannah T. Nickles
  • Migle Sumkauskaite
  • Xin Wang
  • Ingmar Wegner
  • Michael Puderbach
  • Wolfgang M. Kuebler
چکیده

Hannah T. Nickles, Migle Sumkauskaite, Xin Wang, Ingmar Wegner, Michael Puderbach, and Wolfgang M. Kuebler Institute of Physiology, Charité, Universitaetsmedizin Berlin, Germany; German Cancer Research Center Heidelberg, Heidelberg, Germany; Chest Clinic Heidelberg, Heidelberg, Germany; Departments of Surgery and Physiology, University of Toronto, Toronto, Ontario, Canada; The Keenan Research Center for Biomedical Science of St. Michael’s, Toronto, Ontario, Canada

منابع مشابه

Mechanical ventilation causes airway distension with proinflammatory sequelae in mice.

The pathogenesis of ventilator-induced lung injury has predominantly been attributed to overdistension or mechanical opening and collapse of alveoli, whereas mechanical strain on the airways is rarely taken into consideration. Here, we hypothesized that mechanical ventilation may cause significant airway distension, which may contribute to the pathological features of ventilator-induced lung in...

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تاریخ انتشار 2014